A requirement for Zn2+ for the induction of thymidine kinase but not ornithine decarboxylase in 3T3 cells stimulated from quiescence
| Autor: | A J Travis, L Petrie, John K. Chesters |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Ribosomal Proteins
medicine.medical_specialty Thymidine kinase activity Iron Biology Ornithine Decarboxylase Thymidine Kinase Biochemistry 3T3 cells Cell Line Ornithine decarboxylase Mice Internal medicine medicine Animals RNA Messenger Molecular Biology Ribosomal Protein S6 Messenger RNA G0 phase Cell Biology Pentetic Acid Kinetics Zinc Endocrinology medicine.anatomical_structure Cell culture Thymidine kinase Enzyme Induction Ribosomal protein s6 Research Article |
| Zdroj: | Biochemical Journal. 272:525-527 |
| ISSN: | 1470-8728 0264-6021 |
| DOI: | 10.1042/bj2720525 |
| Popis: | In 3T3 cells stimulated from quiescence by serum, impaired thymidine incorporation caused by inadequate supply of Zn2+ was associated with both decreased thymidine kinase activity and a comparable decrease in its mRNA concentration. In contrast, the amount of mRNA for ribosomal protein S6 was not affected, nor was the earlier increase in the activity of ornithine decarboxylase. |
| Databáze: | OpenAIRE |
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