Combined granulomatous and lymphocytic hypophysitis presenting as pituitary incidentaloma in a middle-aged woman
| Autor: | Srishti Gupta, Sandeep Kharb, Reena Bharwaj, HC Pathak, MK Garg, K. S. Brar, Abhay Gundgurthi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Pathology
medicine.medical_specialty Pituitary macroadenoma Hypophysitis Endocrinology Diabetes and Metabolism Case Report with Review of Literature Physical examination Sellar mass lcsh:Diseases of the endocrine glands. Clinical endocrinology Resection Endocrinology Medicine lymphocytic hypophysitis lcsh:RC799-869 incidentaloma lcsh:RC648-665 medicine.diagnostic_test business.industry Incidentaloma Granulomatous hypophysitis medicine.disease Autoimmune hypophysitis lcsh:Diseases of the digestive system. Gastroenterology Radiology business Pituitary incidentaloma |
| Zdroj: | Indian Journal of Endocrinology and Metabolism, Vol 16, Iss 5, Pp 846-849 (2012) Indian Journal of Endocrinology and Metabolism |
| ISSN: | 2230-9500 2230-8210 |
| Popis: | We report a case of 41-year-old lady who presented with chronic headache of 6-month duration and a sellar mass with a suprasellar extension on imaging, which was interpreted as pituitary macroadenoma. She had normal pituitary function and visual perimetry. On clinical examination and imaging it was provisionally diagnosed as pituitary incidentaloma due to hypophysitis and she was advised steroid therapy, but underwent transnasal resection of the tumor against suggestion. Histopathological examination revealed combined granulomatous and lymphocytic hypophysitis most likely of autoimmune in origin. Definitive diagnosis of hypophysitis can be made only on histopathological examination. As most cases of autoimmune hypophysitis are surgically treated, patients should be assessed on individual basis for requirement of steroids in postoperative period. |
| Databáze: | OpenAIRE |
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