Propiconazole inhibits the sterol 14α-demethylase in Glomus irregulare like in phytopathogenic fungi
| Autor: | Anne Grandmougin-Ferjani, Djouher Debiane, Estelle Campagnac, Joël Fontaine, Frédéric Laruelle, Anissa Lounès-Hadj Sahraoui, Maryline Calonne |
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| Rok vydání: | 2011 |
| Předmět: |
Environmental Engineering
Health Toxicology and Mutagenesis Fungus Plant Roots Microbiology Chicory chemistry.chemical_compound Sterol 14-Demethylase Mycorrhizae polycyclic compounds Environmental Chemistry Soil Pollutants Sterol metabolism Glomeromycota Glomus chemistry.chemical_classification biology fungi Public Health Environmental and Occupational Health General Medicine General Chemistry Triazoles biology.organism_classification Pollution Sterol Fungicide Propiconazole Enzyme chemistry Biochemistry 14-alpha Demethylase Inhibitors biology.protein Demethylase lipids (amino acids peptides and proteins) |
| Zdroj: | Chemosphere. 87(4) |
| ISSN: | 1879-1298 |
| Popis: | The increasing concentrations impact (0.02, 0.2 and 2 mg L(-1)) of a Sterol Biosynthesis Inhibitor (SBI) fungicide, propiconazole, was evaluated on development and sterol metabolism of two non-target organisms: mycorrhizal or non-mycorrhizal transformed chicory roots and the arbuscular mycorrhizal fungus (AMF) Glomus irregulare using monoxenic cultures. In this work, we provide the first evidence of a direct impact of propiconazole on the AMF by disturbing its sterol metabolism. A significant decrease in end-products sterols contents (24-methylcholesterol and in 24-ethylcholesterol) was observed concomitantly to a 24-methylenedihydrolanosterol accumulation indicating the inhibition of a key enzyme in sterol biosynthesis pathway, the sterol 14α-demethylase like in phytopathogenic fungi. A decrease in end-product sterol contents in propiconazole-treated roots was also observed suggesting a slowing down of the sterol metabolism in plant. Taken together, our findings suggest that the inhibition of the both AM symbiotic partners development by propiconazole results from their sterol metabolism alterations. |
| Databáze: | OpenAIRE |
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