In VitroAntimicrobial, Antioxidant, and Antispasmodic Activities and the Composition of the Essential Oil ofOriganum acutidens(Hand.-Mazz.) Ietswaart

Autor: Ismihan Goze, Ahmet Ataş, Ahmet Alim, Nedim Durmus, Senay Akkus Cetinus, Ali Cetin, Nilüfer Vural
Přispěvatelé: [Goze, Ismihan] Cumhuriyet Univ, Vocat Sch Hlth Serv, Sivas, Turkey -- [Alim, Ahmet] Cumhuriyet Univ, Fac Sci & Letters, Publ Hlth Lab, Sivas Directorate Hlth, Sivas, Turkey -- [Cetin, Ali] Cumhuriyet Univ, Sch Med, Dept Obstet & Gynecol, Sivas, Turkey -- [Durmus, Nedim] Cumhuriyet Univ, Sch Med, Dept Pharmacol, Sivas, Turkey -- [Atas, Ahmet Turan] Tokat Directorate Hlth, Publ Hlth Lab, Tokat, Turkey -- [Vural, Nilufer] Ankara Univ, BITAUM, Ankara Univ Sci & Technol Res & Applicat Ctr, TR-06100 Ankara, Turkey, Cetin, Ali -- 0000-0002-5767-7894, VURAL, Nilufer -- 0000-0003-3047-3004, Atas, Ahmet -- 0000-0002-8673-6793
Rok vydání: 2010
Předmět:
Zdroj: Journal of Medicinal Food. 13:705-709
ISSN: 1557-7600
1096-620X
DOI: 10.1089/jmf.2009.0094
Popis: WOS: 000278400600031
PubMed ID: 20438322
The radical scavenging, antimicrobial, and antispasmodic activities and the composition of Origanum acutidens (Hand.-Mazz.) Ietswaart (Order Labiatte) essential oil were evaluated in vitro. Gas chromatography/mass spectrometry analysis of the oil resulted in the identification of 20 compounds, representing 93.61% of the oil; carvacrol (65%) was the main component. The sample was also subjected to a screening for antioxidant activity by using the 1,1-diphenyl-2-picrylhydrazyl and beta-carotene/linoleic acid assays. The essential oil exhibited strong antioxidant activity. Using the agar disk diffusion method, antimicrobial activities of the essential oils were determined for nine microorganisms; antimicrobial activity was shown against eight of them. O. acutidens oil exhibited spontaneous contractions in rat ileum at the 100% level at 0.1 mg/mL level.
Databáze: OpenAIRE