Changes in carbohydrate metabolism during 30 months on Norplant
| Autor: | J C Konje, O.A. Ladipo, Emmanuel O. Otolorin |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty Time Factors medicine.medical_treatment Population Levonorgestrel Carbohydrate metabolism Fasting insulin Internal medicine Contraceptive Agents Female Medicine Humans Insulin skin and connective tissue diseases education Drug Implants education.field_of_study Glucose tolerance test medicine.diagnostic_test business.industry Norgestrel Obstetrics and Gynecology Metabolism Carbohydrate Glucose Tolerance Test Endocrinology Reproductive Medicine Carbohydrate Metabolism Female sense organs business medicine.drug |
| Zdroj: | Contraception. 44(2) |
| ISSN: | 0010-7824 |
| Popis: | During a 30-month period, changes in carbohydrate metabolism (measured by oral glucose tolerance test) were studied in 20 Norplant R acceptors. Changes were first observed one month after Norplant R insertion and peaked between 12–18 months. The area under the glucose curve rose by 12.3% and 40.5% one and 12 months post insertion, respectively. At 18, 24 and 30 months the rise was, respectively, 41.9%, 40% and 38.6%. Although the changes under the insulin curves were similar, the increase at one month was doubled (25.7%). Only fasting insulin values showed very slight and insignificant changes during the 30-month period. All the changes were, however, within the normal limits for healthy women. We conclude that although Norplant R induces changes in carbohydrate metabolism, these changes remain within normal limits, peak at 12 months and either remain the same or decrease with time. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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