National study on the utilization of prophylactic antibiotics in surgery, Belgium, 1986
| Autor: | A Stroobant, L Berghmans, Ludo Verbist, Georges Wauters, F Dondeyne, R Mertens, Catherine Potvliege, Gerald Reybrouck, Gerda Verschraegen, B. Gordts, S Lauwers |
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| Jazyk: | angličtina |
| Rok vydání: | 1989 |
| Předmět: |
medicine.medical_specialty
Epidemiology medicine.drug_class Premedication Antibiotics Postoperative Complications Belgium Risk Factors Acute care Medicine Humans Multicenter Studies as Topic Prospective Studies Antibiotic prophylaxis Medical prescription Prospective cohort study Aged business.industry Articles Bacterial Infections Middle Aged Antimicrobial Surgery Anti-Bacterial Agents Infectious Diseases business Complication |
| Popis: | SUMMARYDuring the last week of May 1986, a 1-week prospective study on antibiotic utilization in surgical patients was held in 104 (42%) of the 247 Belgian acute care hospitals. All surgical patients with a post-operative stay of at least 3 days were studied, involving 3112 patients. Each patient was observed for 7 days, starting from the day before surgery. Antibiotics were administered to 71·9% of all patients; 21·9% received therapeutic antibiotics and 52·9% prophylactic antibiotics; 2·9% received both. Of the 1285 patients undergoing a surgical procedure with no indication for antimicrobial prophylaxis, 50·7% nevertheless received prophylaxis; 92·8% of patients with a generally recognized indication for prophylaxis received antibiotic prophylaxis. Less than one fifth (17·1 %) of all prophylactic courses were stopped on the day of the intervention whilst 26·3% were continued up to the fifth post-operative day or beyond. The most frequently prescribed drugs for this indication included first and second generation cephalosporins and nitroimidazoles. The number of different generic drugs utilized per hospital ranged from 1 to 18 (mean: 7·7). |
| Databáze: | OpenAIRE |
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