Recent Advances and Future Prospects in Bacterial and Archaeal Locomotion and Signal Transduction
| Autor: | Sonia L. Bardy, Simon Rainville, Tino Krell, Ariane Briegel |
|---|---|
| Přispěvatelé: | Ministerio de Economía y Competitividad (España) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
030106 microbiology Population ved/biology.organism_classification_rank.species Motility Flagellum flagellar motility Microbiology 03 medical and health sciences chemotaxis education Model organism Molecular Biology Organism education.field_of_study biology ved/biology two-component regulatory systems Chemotaxis biology.organism_classification Meeting Review Cell biology Biophysics flagella Signal transduction Bacteria signal transduction |
| Zdroj: | Journal of Bacteriology, 199(18), e00203 Journal of Bacteriology Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | The structure and function of two-component and chemotactic signaling and different aspects related to the motility of bacteria and archaea are key research areas in modern microbiology. Escherichia coli is the traditional model organism used to study chemotaxis signaling and motility. However, the recent study of a wide range of bacteria and even some archaea with different lifestyles has provided new insight into the ecophysiology of chemotaxis, which is essential for the establishment of different pathogens or beneficial bacteria in a host. The expanded range of model organisms has also permitted the study of chemosensory pathways unrelated to chemotaxis, multiple chemotaxis pathways within an organism, and new types of chemoreceptors. This research has greatly benefitted from technical advances in the field of cryomicroscopy, which continues to reveal with increasing resolution the complexity and diversity of large protein complexes like the flagellar motor or chemoreceptor arrays. In addition, sensitive instruments now allow an increasing number of experiments to be conducted at the single-cell level, thereby revealing information that is beginning to bridge the gap between individual cells and population behavior. Evidence has also accumulated showing that bacteria have evolved different mechanisms for surface sensing, which appears to be mediated by flagella and possibly type IV pili, and that the downstream signaling involves chemosensory pathways and two-component-system-based processes. Herein, we summarize the recent advances and research tendencies in this field as presented at the latest Bacterial Locomotion and Signal Transduction (BLAST XIV) conference. Research in our laboratories is supported by grants from the Spanish Ministry for Economy and Competitiveness (grants BIO2013-42297 and 585 BIO2016-76779-P to T.K.) and the Canada Foundation for Innovation (SR). |
| Databáze: | OpenAIRE |
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