Increasing prevalence of hypertension among HIV-positive and negative adults in Senegal, West Africa, 1994-2015

Autor: Macoumba Toure, Marie Pierre Sy, Ibrahima N. Doye, Papa Salif Sow, Nancy B. Kiviat, Stephen E. Hawes, Noelle A. Benzekri, Moussa Seydi, Geoffrey S. Gottlieb
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Physiology
Epidemiology
HIV Infections
Blood Pressure
Disease
030204 cardiovascular system & hematology
Logistic regression
Severity of Illness Index
Vascular Medicine
Body Mass Index
Geographical Locations
0302 clinical medicine
Prevalence
030212 general & internal medicine
Young adult
Aged
80 and over
Multidisciplinary
Age Factors
Middle Aged
Senegal
3. Good health
Physiological Parameters
HIV epidemiology
Hypertension
Medicine
Female
Research Article
Adult
Adolescent
Science
Young Adult
03 medical and health sciences
Sex Factors
Severity of illness
medicine
Humans
Obesity
cardiovascular diseases
Risk factor
Aged
Retrospective Studies
Medicine and health sciences
business.industry
Body Weight
Correction
Biology and Life Sciences
Retrospective cohort study
medicine.disease
Logistic Models
Medical Risk Factors
People and Places
Africa
business
Body mass index
Demography
Zdroj: PLoS ONE, Vol 13, Iss 12, p e0208635 (2018)
PLoS ONE
ISSN: 1932-6203
Popis: BackgroundNon-communicable diseases, including hypertension (HTN), are increasingly recognized as important causes of morbidity and mortality among people living with HIV (PLHIV) in resource-limited settings. The goals of this study were to determine the prevalence of HTN among PLHIV in Senegal over time and to identify predictors of HTN among HIV-positive versus HIV-negative adults.MethodsWe conducted a retrospective study using data from individuals enrolled in previous studies in Senegal from 1994-2015. Blood pressure (BP) measurements taken during study visits were used for analysis. HTN was defined as systolic BP≥140 or diastolic BP≥90. We used logistic regression to identify predictors of HTN.ResultsWe analyzed data from 2848 adults (1687 HIV-positive, 1161 HIV-negative). Among PLHIV, the prevalence of HTN increased from 11% during 1994-1999 to 22% during 2010-2015. Among HIV-negative individuals, the prevalence of HTN increased from 16% to 32%. Among both groups, the odds of HTN more than doubled from 1994-1999 to 2010-2015 (HIV-positive OR 2·4, 95% CI 1·1-5·0; HIV-negative OR 2·6, 95% CI 1·5-4·6). One quarter of all individuals with HTN had stage 2 HTN. The strongest risk factor for HTN was obesity (HIV-positive OR 3·2, 95% CI 1·7-5·8; pConclusionOver the past 20 years, the prevalence of HTN has doubled among both HIV-positive and HIV-negative adults in Senegal. Our study indicates that there is an increasing need for the integration of chronic disease management into HIV programs in Senegal. Furthermore, our findings highlight the need for enhanced prevention, recognition, and management of non-communicable diseases, including hypertension and obesity, among both HIV-positive and HIV-negative individuals in Senegal.
Databáze: OpenAIRE
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