Effects of a New Patient Safety-Driven Oxytocin Dosing Protocol on Postpartum Hemorrhage
| Autor: | Jiri Sonek, Kari Rudinsky, David S. McKenna |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Blood transfusion Article Subject medicine.medical_treatment Oxytocin lcsh:Gynecology and obstetrics Cohort Studies Hemoglobins Clinical Protocols Pregnancy Oxytocics Humans Medicine Blood Transfusion Dosing lcsh:RG1-991 Retrospective Studies business.industry Postpartum Hemorrhage A hemoglobin Obstetrics and Gynecology Retrospective cohort study medicine.disease Treatment Outcome Anesthesia Clinical Study Female Patient Safety Hemoglobin business medicine.drug Cohort study |
| Zdroj: | Journal of Pregnancy, Vol 2014 (2014) Journal of Pregnancy |
| ISSN: | 2090-2735 2090-2727 |
| Popis: | Objective.To determine if there was an increase in postpartum (PP) hemorrhage after decreasing the PP oxytocin dose from 40 to 30 units.Study Design.Retrospective cohort study comparing 8 months before to 8 months after the change. PP day 1 hemoglobin was subtracted from admission hemoglobin. Mean change was compared by Student’st-test. The best fit polynomial was analyzed for trends between the two time frames. Women who received blood transfusions were excluded.Results.73/3564 (2.0%) women received blood transfusions in the pre group and 64/3295 (1.9%) women in the post group,P=0.8. Mean hemoglobin change ± standard deviation was1.53±0.03 g/dL for pre versus1.52±0.05 g/dL for post,P=0.68. 1003/3114 (32.2%) in the pre group had a hemoglobin decrease of ≥2 g/dL compared to 918/2895 (31.7%) in the post group,P=0.7. 261/3114 (8.4%) in the pre group had a hemoglobin decrease of ≥3 g/dL compared to 252/2895 (8.7%),P=0.7. There were no significant trends between the two time frames.Conclusion.The change in the dose of PP oxytocin did not result in an increase in postpartum hemorrhage or an increase in the need for blood transfusion. |
| Databáze: | OpenAIRE |
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