Vaccination as a possible means of preventing lantana poisoning
| Autor: | J A Lamberton, C Stewart, Pass, R J Fairclough |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Sapogenins
medicine.medical_treatment Lantana camara Cattle Diseases Sheep Diseases Lantana Antibodies Microbiology Cholestasis medicine Animals Oleanolic Acid Bovine serum albumin Plant Poisoning Sheep General Veterinary biology Vaccination Lantadene B General Medicine medicine.disease biology.organism_classification Triterpenes biology.protein Cattle Antibody Adjuvant |
| Zdroj: | Australian Veterinary Journal. 65:349-352 |
| ISSN: | 1751-0813 0005-0423 |
| DOI: | 10.1111/j.1751-0813.1988.tb14262.x |
| Popis: | The toxic triterpene acids lantadene A and lantadene B were isolated from Lantana camara and conjugated to bovine serum albumen or haemocyanin. The conjugates were emulsified with complete Freund's adjuvant and injected into sheep and cattle. Vaccinated animals produced antibodies against the toxic compounds. Cholestasis was less severe in vaccinated than in non-vaccinated sheep challenged with a toxic dose of lantana. The results indicated a mild protective effect of vaccination against the hepatotoxic effects of lantana toxins. |
| Databáze: | OpenAIRE |
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