| Autor: |
Xianxin Hua, Donita C. Brady, Bruce D. Freedman, Xin He, Yuan Wu, Haoren Wang, Yuanyuan Liu, Smita Matkar, Katherine M. Szigety, Corbett T. Berry, Jian Ma, Caroline I. Davis, Zijie Feng, Kayla E. Paulosky, Rebecca A. Glynn, Bryson W. Katona |
| Rok vydání: |
2023 |
| Popis: |
Supplemental Figure S1: Menin inhibition has minimal effects on cell growth in colon cancer cells. Supplemental Figure S2: Inhibition of menin selectively sensitizes colon cancer cells to iEGFRs. Supplemental Figure S3: BAPTA rescues cells from the combination of gefitinib plus MI-2-2. Supplemental Figure S4: SERCA2 over-expression rescues cells from thapsigargin but not gefitinib. Supplemental Figure S5: Gefitinib induced CRC suppression is mediated by activation of IP3R3. Supplemental Figure S6: Menin inhibition, gefitinib, and TG all decrease SKP2 levels. Supplemental Figure S7: Regulation of SKP2 transcription by menin and intracellular calcium levels. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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