Deuterium nuclear spin relaxation in biological tissues

Autor:	Ronald E. Block, Barbara C. Parekh
Rok vydání:	1987
Předmět:	Magnetic Resonance Spectroscopy Correlation coefficient Proton Chemistry Relaxation (NMR) Analytical chemistry Oxide Deuterium Rats chemistry.chemical_compound Nuclear magnetic resonance Animals Radiology Nuclear Medicine and imaging
Zdroj:	Magnetic Resonance in Medicine. 5:286-289
ISSN:	1522-2594 0740-3194
DOI:	10.1002/mrm.1910050310
Popis:	The deuterium nuclear spin relaxation times have been measured in tissues taken from rats given 20% deuterium oxide in their drinking water. The spin–lattice and spin–spin relaxation times were measured at 13.7 MHz by the inversion–recovery and Carr–Purcell–Meiboom–Gill FT methods, respectively. The reciprocals of the spin–lattice (T1) relaxation times were found to correlate well with those of protons in similar nondeuteriated tissues at a similar frequency (13.6 MHz) measured in a separate study. A least-squares analysis of the data yields (I/Tl)II = (0.991)(I/T1)D – 3.48 for five tissues (standard deviations of 0.097 for the slope and 0.383 for the intercept with a correlation coefficient of 0.986). Implications with respect to relaxation mechanisms are discussed. 0_1987 Academic Press, Inc.
Databáze:	OpenAIRE
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