Verification of Accuracy of CyberKnife Tumor-tracking Radiation Therapy Using Patient-specific Lung Phantoms
| Autor: | Wonsik Choi, KyoungJun Yoon, Jungwon Kwak, Seong-Yun Jeong, Sang Min Yoon, Eun Kyung Choi, Jinhong Jung, Si Yeol Song, Byungchul Cho |
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| Rok vydání: | 2015 |
| Předmět: |
Cancer Research
medicine.medical_specialty Lung Neoplasms Polymers Movement Polyesters medicine.medical_treatment Radiosurgery Standard deviation Fiducial Markers Cyberknife Carcinoma Non-Small-Cell Lung Hounsfield scale Medical Illustration Humans Medicine Radiology Nuclear Medicine and imaging Lactic Acid Radiometry Lung cancer Lung Radiation Phantoms Imaging business.industry Radiotherapy Planning Computer-Assisted Respiration Radiotherapy Dosage Patient specific medicine.disease Tumor Burden Radiation therapy medicine.anatomical_structure Surgery Computer-Assisted Oncology Printing Three-Dimensional Radiology business Fiducial marker Nuclear medicine |
| Zdroj: | International Journal of Radiation Oncology*Biology*Physics. 92:745-753 |
| ISSN: | 0360-3016 |
| Popis: | Purpose To investigate the accuracy of the CyberKnife Xsight Lung Tracking System (XLTS) compared with that of a fiducial-based target tracking system (FTTS) using patient-specific lung phantoms. Methods and Materials Three-dimensional printing technology was used to make individualized lung phantoms that closely mimicked the lung anatomy of actual patients. Based on planning computed tomographic data from 6 lung cancer patients who underwent stereotactic ablative radiation therapy using the CyberKnife, the volume above a certain Hounsfield unit (HU) was assigned as the structure to be filled uniformly with polylactic acid material by a 3-dimensional printer (3D Edison, Lokit, Korea). We evaluated the discrepancies between the measured and modeled target positions, representing the total tracking error, using 3 log files that were generated during each treatment for both the FTTS and the XLTS. We also analyzed the γ index between the film dose measured under the FTTS and XLTS. Results The overall mean values and standard deviations of total tracking errors for the FTTS were 0.36 ± 0.39 mm, 0.15 ± 0.64 mm, and 0.15 ± 0.62 mm for the craniocaudal (CC), left–right (LR), and anteroposterior (AP) components, respectively. Those for the XLTS were 0.38 ± 0.54 mm, 0.13 ± 0.18 mm, and 0.14 ± 0.37 mm for the CC, LR, and AP components, respectively. The average of γ passing rates was 100% for the criteria of 3%, 3 mm; 99.6% for the criteria of 2%, 2 mm; and 86.8% for the criteria of 1%, 1 mm. Conclusions The XLTS has segmentation accuracy comparable with that of the FTTS and small total tracking errors. |
| Databáze: | OpenAIRE |
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