Stem cell-related therapies for vascular diseases
| Autor: | John A. Snowden, S. M. Watt, E. Martin-Rendon |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Clinical Trials as Topic
business.industry Bone Marrow Stem Cell Hematology Coronary Artery Disease Bioinformatics Clinical trial Cell therapy Transplantation Haematopoiesis Adult Stem Cells medicine.anatomical_structure Immunology Medicine Animals Humans Bone marrow Stem cell business Adult stem cell Stem Cell Transplantation |
| Zdroj: | Transfusion medicine (Oxford, England). 19(4) |
| ISSN: | 1365-3148 0958-7578 |
| Popis: | summary. The therapeutic potential of ‘adult’ or at least non-embryonic stem cells and their progeny has developed gradually over the past half century as a consequence of the wealth of knowledge derived from stem cell research. Translational research coupled with clinical trials and derived from basic research has led the way to the clinic. This commenced with the use of haematopoietic stem cell transplantation (HSCT), to treat haematological malignancies, to be followed by the most recent clinical trials to treat a variety of coronary and peripheral artery diseases. Stem cells and their progeny isolated from bone marrow or blood appear to exert an ameliorating effect in certain vascular disorders. Although promising, some of these treatments remain controversial and further research and, where indicated, appropriately powered trials are required to confirm the safety and determine the efficacy of these novel therapies. |
| Databáze: | OpenAIRE |
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