Physiological changes of Fas expression in peripheral lymphocyte subsets during the menstrual cycle
| Autor: | Yukiyo Nakamura, Yoshinori Iwatani, Rie Shinoda, Yukari Kimura, Hayato Maruoka, Mikio Watanabe |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty media_common.quotation_subject Immunology CD8-Positive T-Lymphocytes Luteal Phase Luteal phase Biology Natural killer cell Flow cytometry Pregnancy Internal medicine Follicular phase medicine Humans Immunology and Allergy fas Receptor Menstrual Cycle reproductive and urinary physiology Menstrual cycle media_common medicine.diagnostic_test urogenital system Obstetrics and Gynecology T lymphocyte Flow Cytometry Lymphocyte Subsets Killer Cells Natural Endocrinology medicine.anatomical_structure Follicular Phase Reproductive Medicine Female Tumor necrosis factor alpha hormones hormone substitutes and hormone antagonists CD8 |
| Zdroj: | Journal of Reproductive Immunology. 60:159-168 |
| ISSN: | 0165-0378 |
| DOI: | 10.1016/s0165-0378(03)00107-4 |
| Popis: | We have examined changes in peripheral lymphocyte subsets, and Fas expression in these subsets, during the menstrual cycle. Measurements were made by three-color flow cytometry in the follicular and luteal phases of the menstrual cycle in ten healthy women. The numbers of leukocytes, granulocytes and monocytes were significantly higher in the luteal phase than the follicular phase. The percentage of CD8 + cells was greater in the luteal phase than the follicular phase. The percentages of Fas + cells among T cells and NK cells were higher in the luteal phase than the follicular phase. These findings suggest that the menstrual cycle affects leukocytes, lymphocyte subsets, and Fas expression in these subsets, and that changes in the luteal phase of the menstrual cycle are similar to those in pregnancy. |
| Databáze: | OpenAIRE |
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