Acrodermatitis Chronica Atrophicans: Histopathologic Findings and Clinical Correlations in 111 Cases
| Autor: | Eva Åsbrink, Eva Brehmer-Andersson, Anders Hovmark |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Biopsy Plasma Cells Dermatology Lymphatic System Perineural Cell Nerve Fibers Atrophy Fibrosis medicine Edema Humans Lymphocytes Aged Skin Aged 80 and over Sclerosis medicine.diagnostic_test Histocytochemistry business.industry Acrodermatitis General Medicine Middle Aged medicine.disease Allodynia Lymphatic system Epidermal Cells Blood Vessels Female Epidermis medicine.symptom Borrelia Infections business Acrodermatitis chronica atrophicans |
| Zdroj: | Acta Dermato-Venereologica. 78:207-213 |
| ISSN: | 0001-5555 |
| DOI: | 10.1080/000155598441558 |
| Popis: | We studied 111 consecutive, untreated and serologically confirmed patients with acrodermatitis chronica atrophicans. Emphasis was on the histopathologic patterns of erythematous and fibrous lesions, and on an assay used to correlate histopathologic findings with such clinical features as fibrous nodules, ulnar bands and the pain reaction allodynia. There was a significant correlation between allodynia and signs of marked inflammation, but not between allodynia and neural and perineural cell infiltrates or fibrosis. Moreover, there was no significant correlation between serum IgG titers to Borrelia and the density of inflammatory cell infiltrates or the proportion of plasma cells in tissue. Histopathologic examination did not reveal any important differences between fibrous nodules, ulnar bands and sclerodermatous lesions. The histopathologic pattern is not diagnostic per se, but characteristic enough to alert the experienced pathologist. |
| Databáze: | OpenAIRE |
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