ATAB2 is a novel factor in the signalling pathway of light-controlled synthesis of photosystem proteins

Autor: Jean-David Rochaix, Veronika Winter, Fredy Barneche, Michèle Crèvecœur
Rok vydání: 2006
Předmět:
Chloroplasts
Light
Transcription
Genetic
Arabidopsis
Seedling/growth & development/radiation effects
Mutant Proteins/metabolism
Gene Expression Regulation
Plant
Exons/genetics
Protein biosynthesis
Photosystem I Protein Complex/biosynthesis
Photosystem
Photoreceptor Cells/metabolism
Arabidopsis Proteins/genetics/metabolism
Plant Leaves/radiation effects/ultrastructure
General Neuroscience
food and beverages
RNA-Binding Proteins
Exons
Plants
Genetically Modified
Arabidopsis/genetics/growth & development/metabolism/radiation effects
Cell biology
Chloroplast
ddc:580
Phenotype
Thylakoid
Poly A-U/metabolism
Chloroplasts/radiation effects/ultrastructure
Signal Transduction
Mutation/genetics
RNA
Messenger/genetics/metabolism
Protein subunit
Biology
Photosystem I
General Biochemistry
Genetics and Molecular Biology
Article
ddc:570
Protein Biosynthesis/radiation effects
Animals
Photoreceptor Cells
RNA
Messenger
RNA-Binding Proteins/genetics/metabolism
Molecular Biology
Polyribosomes/radiation effects
General Immunology and Microbiology
Photosystem I Protein Complex
Arabidopsis Proteins
Chlamydomonas
Photosystem II Protein Complex
biology.organism_classification
Molecular biology
Photosystem II Protein Complex/biosynthesis
Plant Leaves
Mutagenesis
Insertional
Gene Expression Regulation
Plant/radiation effects
Seedlings
Polyribosomes
Protein Biosynthesis
Mutation
Transcription
Genetic/radiation effects
Poly A-U
Mutant Proteins
Zdroj: EMBO Journal, Vol. 25, No 24 (2006) pp. 5907-18
ISSN: 0261-4189
Popis: Plastid translational control depends to a large extent on the light conditions, and is presumably mediated by nucleus-encoded proteins acting on organelle gene expression. However, the molecular mechanisms of light signalling involved in translation are still poorly understood. We investigated the role of the Arabidopsis ortholog of Tab2, a nuclear gene specifically required for translation of the PsaB photosystem I subunit in the unicellular alga Chlamydomonas. Inactivation of ATAB2 strongly affects Arabidopsis development and thylakoid membrane biogenesis and leads to an albino phenotype. Moreover the rate of synthesis of the photosystem reaction center subunits is decreased and the association of their mRNAs with polysomes is affected. ATAB2 is a chloroplast A/U-rich RNA-binding protein that presumably functions as an activator of translation with at least two targets, one for each photosystem. During early seedling development, ATAB2 blue-light induction is lowered in photoreceptor mutants, notably in those lacking cryptochromes. Considering its role in protein synthesis and its photoreceptor-mediated expression, ATAB2 represents a novel factor in the signalling pathway of light-controlled translation of photosystem proteins during early plant development.
Databáze: OpenAIRE
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