Anti-Erosive Effect of Solutions Containing Sodium Fluoride, Stannous Chloride, and Selected Film-Forming Polymers
| Autor: | Anderson T. Hara, Idalina Vieira Aoki, Taís Scaramucci, Samira Helena João-Souza, Sávio José Cardoso Bezerra, Alessandra Bühler Borges |
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| Přispěvatelé: | Universidade de São Paulo (USP), University of Bern, Universidade Estadual Paulista (Unesp), Indiana University School of Dentistry |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Stannous chloride
Alginates Polymers In Vitro Techniques Chloride 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Sodium fluoride medicine Dentin Humans Tooth Erosion 030212 general & internal medicine 610 Medicine & health Fluoride General Dentistry Enamel paint Maleates Povidone Tin Compounds 030206 dentistry medicine.anatomical_structure chemistry Distilled water visual_art Carboxymethylcellulose Sodium visual_art.visual_art_medium Tin Fluorides 570 Life sciences biology Propylene glycol alginate Sodium Fluoride Polyvinyls Dental erosion Citric acid FLUORETO Nuclear chemistry medicine.drug |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Made available in DSpace on 2019-10-06T15:22:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) The aim of this study was to evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225 ppm F), stannous chloride (Sn: 800 ppm Sn2+), and some film-forming polymers (Gantrez: Poly [methylvinylether-alt-maleic anhydride]; PGA: propylene glycol alginate; Plasdone: poly[vinylpyrrolidone]; and CMC: carboxymethylcellulose). Solutions were tested in an erosion-remineralization cycling model, using enamel and dentin specimens (n = 10, for each substrate). Distilled water was the negative control. Cycling consisted of 120 min immersion in human saliva, 5 min in 0.3% citric acid solution, and 120 min of exposure to human saliva, 4×/day, for 5 days. Treatment with solutions (pH = 4.5) was carried out 2×/day, for 2 min. Surface loss (SL) was evaluated with optical profilometry. Zeta potential of hydroxyapatite crystals was determined after treatment with the solutions. Data were statistically analyzed (α = 0.05). For enamel, all polymers showed significantly lower SL (in μm) than the control (11.09 ± 0.94), except PGA (10.15 ± 1.25). PGA significantly improved the protective effect of F (4.24 ± 0.97 vs. 5.64 ± 1.60, respectively). None of the polymers increased the protection of F+Sn (5.13 ± 0.78). For dentin, only Gantrez (11.40 ± 0.97) significantly reduced SL when compared with the negative control (12.76 ± 0.75). No polymer was able to enhance the effect of F (6.28 ± 1.90) or F+Sn (7.21 ± 1.13). All fluoridated solutions demonstrated significantly lower SL values than the control for both substrates. Treatment of hydroxyapatite nanoparticles with all solutions resulted in more negative zeta potentials than those of the control, except Plasdone, PGA, and F+Sn+PGA, the latter two presenting the opposite effect. In conclusion, Gantrez, Plasdone, and CMC exhibited an anti-erosive effect on enamel. PGA increased the protection of F. For dentin, only Gantrez reduced erosion. Department of Restorative Dentistry School of Dentistry University of São Paulo Department of Restorative Preventive and Pediatric Dentistry School of Dental Medicine University of Bern Department of Chemical Engineering Polytechnic School São Paulo University - USP Department of Restorative Dentistry Institute of Science and Technology São Paulo State University - UNESP Department of Cariology Operative Dentistry and Dental Public Health Indiana University School of Dentistry Department of Restorative Dentistry Institute of Science and Technology São Paulo State University - UNESP FAPESP: #2015/11402-8 |
| Databáze: | OpenAIRE |
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