Passive hemolytic antibody response of primed, partially resistant mice to heat-killed Salmonella typhimurium vaccine
| Autor: | John P. Ransom |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Salmonella typhimurium
Salmonella Lipopolysaccharide business.industry Partial immunity Time optimal medicine.disease_cause Virology Effective dose (pharmacology) General Biochemistry Genetics and Molecular Biology Microbiology Bacterial vaccine Antigen-Antibody Reactions chemistry.chemical_compound Mice Antibody response chemistry Antibody Formation Bacterial Vaccines Methods Medicine Animals Serologic Tests business Killed Vaccine |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 128(2) |
| ISSN: | 0037-9727 |
| Popis: | SummaryMean effective doses (50% protection) of S. typhimurium heat-killed, alcohol-treated bacterial vaccine depended upon the interval before challenge at which the single dose was given. Circulating antibody response against the lipopolysaccharide component of the organism appeared to be related to the magnitude of the mean effective dose, but not to the partial immunity developed. Killed vaccine was an effective immunizing agent if given at an optimal time interval before challenge. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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