Primary cardiogenic shock during acute myocardial infarction: results of emergency cardiac transplantation

Autor: G. Dureau, Canu G, Ph. Chevalier, Champagnac D, Gilbert Kirkorian, M. Chuzel, Desseigne P, L. Lyon, Jacques Ninet, J. Ph. Claudel, P. Touboul
Rok vydání: 1993
Předmět:
Zdroj: European heart journal. 14(7)
ISSN: 0195-668X
Popis: Fifteen patients with acute myocardial infarction and cardiogenic shock underwent emergency cardiac transplantation after medical treatment failed to improve their haemodynamic status. Their mean age was 49 +/- 7 years. The infarction was anterior in 12 cases, inferoposterior in two cases, and septal in one. Shock occurred within 3 days after the onset of chest pain in nine patients, and during the first day in six of them. Mechanical circulatory assistance was used in six patients as a bridge to transplantation when their haemodynamic status could not be stabilized pharmacologically. Orthotopic cardiac transplantation was performed an average of 15.6 +/- 14 days after onset of infarction. Three patients died during the early post-operative period. Another died 7 months after transplantation. During the mean follow-up period of 30.6 +/- 20.3 months, there were three acute rejections, all successfully treated, and one chronic rejection. The survival rate for this series is 70%. Thus, emergency cardiac transplantation may be the best option for selected patients with acute myocardial infarction and cardiogenic shock refractory to conventional therapy.
Databáze: OpenAIRE