One-step fabrication of single-phase hydroxyapatite coatings on Ti-alloy implants by electrostatic spray deposition: From microstructural investigation to in vitro studies
| Autor: | Elisabeth Djurado, Laurent Gremillard, Solène Tadier, Sandra Balvay, Verónica Müller, Claire Gaillard |
|---|---|
| Přispěvatelé: | Matériaux Interfaces ELectrochimie (MIEL), Laboratoire d'Electrochimie et de Physico-chimie des Matériaux et des Interfaces (LEPMI), Institut de Chimie du CNRS (INC)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Institut de Chimie du CNRS (INC)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA), ANR-17-CE19-0004,DECaP,Revêtements phosphocalciques électro-déposés pour applications biomédicales(2017) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Electrostatic spray deposition
Materials science Alloy 02 engineering and technology engineering.material 03 medical and health sciences Crystallinity Coating Phase (matter) Materials Chemistry Ceramic Single-phase hydroxyapatite coatings Osteoblast-like cells 030304 developmental biology 0303 health sciences Titanium alloy Surfaces and Interfaces General Chemistry [CHIM.MATE]Chemical Sciences/Material chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Microstructure In vitro evaluation Surfaces Coatings and Films Ti6Al4V substrate Chemical engineering visual_art engineering visual_art.visual_art_medium Crystallite 0210 nano-technology Microstructural properties |
| Zdroj: | Surface and Coatings Technology Surface and Coatings Technology, Elsevier, 2021, 427, pp.127805. ⟨10.1016/j.surfcoat.2021.127805⟩ |
| ISSN: | 0257-8972 |
| DOI: | 10.1016/j.surfcoat.2021.127805⟩ |
| Popis: | International audience; The intrinsic characteristics of calcium phosphate-based ceramics (composition, crystallinity, morphology) enable them to be successfully used as osseoconductive coatings on load-bearing implants. Among these compounds, hydroxyapatite (HAP) is the leading material owing to its similarity with the mineral component of bone tissue. In this work, electrostatic spray deposition (ESD) using an organic phosphorus precursor was employed as a suitable one-step coating technique that might overcome the drawbacks of the widely used plasma-spraying process related to extremely high processing temperatures, such as unpredictable phase changes of the feedstock, particle release, and delamination. The key ESD parameters (type of the solvent(s), total reagent concentration, nominal Ca/P ratio in the precursor solution, solution flow-rate, substrate temperature, and nozzleto-substrate distance) were systematically studied to tune, precisely, the microstructure and the crystallite size of single-phase HAP coatings on Ti6Al4V substrates. In vitro studies with MG-63 osteoblast-like cells were performed during 24 h exposure to selected ESD-derived HAP coatings. All coatings were found to support cell viability. Moreover, the coating properties, i.e., crystallite size and microstructure, played an extremely important role in the behavior of osteoblast-like cells. A higher cellular response was observed when low crystalline HAP coatings were employed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect