Murine typhus in southern Taiwan during 1992-2009
| Autor: | Hsiao Chen Hsieh, Chia Ming Chang, Tun-Chieh Chen, Chi Jung Wu, Yen-Hsu Chen, Jih-Jin Tsai, Ko Chang, Hsin Chun Lee, Chung Hsu Lai, Chun-Yu Lin, Ping Chang Lai, Nan Yao Lee, Wei Ru Lin, Wen Chien Ko, Po-Liang Lu |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Southern taiwan Taiwan Murine typhus Gastroenterology Mice Young Adult Environmental temperature Virology Internal medicine medicine Animals Humans In patient Young adult Child Aged Hepatitis Aged 80 and over business.industry Aseptic meningitis Bilirubin Typhus Endemic Flea-Borne Articles Middle Aged medicine.disease Infectious Diseases Immunology Parasitology Female business Typhus |
| Zdroj: | The American journal of tropical medicine and hygiene. 87(1) |
| ISSN: | 1476-1645 |
| Popis: | Clinical information regarding murine typhus in Taiwan is limited. In this study, 81 cases of serologically documented murine typhus during 1992-2009 at four referral hospitals in southern Taiwan were analyzed. There was a significant correlation between average environmental temperature and case numbers of murine typhus (r = 0.747, P = 0.005). Acute hepatitis was found in 67% of cases, and hyperbilirubinemia (serum total bilirubin ≥ 23.9 μmol/L) was found in 38%. The intervals between the initiation of appropriate therapy to defervescence were longer in patients with hyperbilirubinemia than those without hyperbilirubinemia (6.1 versus 4.1 days; P = 0.015). Nine (11.1%) showed development of severe illnesses such as acute respiratory distress syndrome (2 patients), aseptic meningitis (3), and acute renal failure (4). Only one died of acute respiratory distress syndrome. Cases of murine typhus were often found during the summer and had acute febrile hepatitis. Those patients with hyperbilirubinemia tended to have a delayed recovery even with appropriate therapy. |
| Databáze: | OpenAIRE |
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