A capillary electrophoresis chip with hydrodynamic sample injection for measurements from a continuous sample flow

Autor: S. Büttgenbach, R. Wilke
Rok vydání: 2005
Předmět:
Zdroj: Analytical and Bioanalytical Chemistry. 383:733-737
ISSN: 1618-2650
1618-2642
Popis: A microchip-based capillary electrophoresis device supported by a microfluidic network made of poly(dimethylsiloxane), used for measuring target analytes from a continuous sample flow, is presented. The microsystem was fabricated by means of replica molding in combination with standard microfabrication technologies, resulting in microfluidic components and an electrochemical detector. A new hydrodynamic sample injection procedure is introduced, and the maximum number of consecutive measurements that can be made with a poly(dimethylsiloxane) capillary electrophoresis chip with amperometric detection is investigated with respect to reproducibility. The device features a high degree of functional integration, so the benefits associated with miniaturized analysis systems apply to it.
Databáze: OpenAIRE