HBsAg, Anti-HCV and Anti-HIV Seroprevalance Among Drug Users: a Retrospective Assessment
| Autor: | Imre Altuglu, Aysin Zeytinoglu, Selin Tanyeri, Ayşe Ender Altıntoprak |
|---|---|
| Přispěvatelé: | Ege Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty HBsAg Population medicine.disease_cause Drug abuse 03 medical and health sciences 0302 clinical medicine Medical microbiology Internal medicine medicine Outpatient clinic 030212 general & internal medicine education Hepatitis B virus Harm reduction education.field_of_study business.industry General Neuroscience virus diseases HIV Retrospective cohort study medicine.disease digestive system diseases Substance abuse Psychiatry and Mental health 030104 developmental biology intravenous hepatitis B hepatitis C business Research Article |
| ISSN: | 0005-0318 |
| Popis: | Tanyeri, Selin/0000-0001-9667-4525 WOS:000503184000006 PubMed: 31523144 Introduction: Drug abuse and co-occurring infections are associated with significant morbidity and mortality. in regions with high rates of drug usage, infections like hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are highly prevalent. Epidemiological studies on HBV, HCV and HIV infections among users of illicit drugs are scarce in Turkey. The primary aim of this cross-sectional and retrospective study was to determine the hepatitis B surface antigen (HBsAg), anti-HCV antibody (anti-HCV) and anti-HIV antibody (anti-HIV) seroprevalences in drug users who applied to a psychiatric outpatient clinic of drug addiction of a university hospital. Secondarily, the assessment of HBsAg, anti-HCV and anti-HIV parameters among intravenous drug users was aimed. Methods: Serum samples of all patients on probation who applied to a psychiatric outpatient clinic of drug addiction of a university hospital between 2013-2017 and sent to the department of medical microbiology for routine serologic testing were included in the study. The serologic results were obtained retrospectively from laboratory records. For the statistical analysis of the data IBM SPSS 20.0 program was used. Results: Among the studied individuals, the ELISA results demonstrated the existence of HBsAg, anti-HCV and anti-HIV in 94 out of 4357 patients (2.2%), 27 out of 4451 patients (0.6%) and 10 (0.2%) out of 4464 patients, respectively. According to the records, 17 of the patients reported intravenous drug usage. Among this patient group, three patients were found to be anti-HCV positive and one patient was found to be anti-HIV positive. Conclusion: in our study, the prevalence of HCV and HIV was increased in patients with intravenous drug usage, whereas in non-intravenous drug users the prevalence is similar to the normal population. in order to plan prevention and harm reduction services for this high-risk population, more national data is needed on HBV, HCV and HIV rates among this group. |
| Databáze: | OpenAIRE |
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