Supplementary Figure 2 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
| Autor: | Kristina A. Cole, John M. Maris, Stuart D. Shumway, Bruce Pawel, Daniel Martinez, Yimei Li, Lili Belcastro, JulieAnn Rader, Kirill Levin, Mike R. Russell |
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| Rok vydání: | 2023 |
| Popis: | PDF file - 48K, Wee1 and Chk1 expression are elevated in high-risk, MYCN-amplified neuroblastoma. Primary tumors were obtained from 251 patients at diagnosis (221 high-risk, 30 low-risk; 68 MYCN amplified, 183 MYCN non-amplified), and were run on Affymetrix Human Exon 1.0 ST expression microarrays. Both Wee1 and Chk1 expression were expressed at a significantly higher rate in both the MYCN amplified and high-risk conditions |
| Databáze: | OpenAIRE |
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