Effect of Gentamicin on Growth of Viral, Chlamydial, and Rickettsial Agents in Mice and Embryonated Eggs
| Autor: | White La, Tzianabos T, Hall He, Chappell Wa |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Male
medicine.drug_class Antibiotics Psittacosis Microbiology Mice medicine Animals Pharmacology (medical) Rickettsia akari Chlamydia Rickettsia Pharmacology Infectivity Mice Inbred ICR biology Lymphogranuloma venereum Embryonated bacterial infections and mycoses medicine.disease biology.organism_classification Pharmacology and Therapeutics Virology Infectious Diseases Viruses Gentamicin Gentamicins medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 10:344-346 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.10.2.344 |
| Popis: | Gentamicin, at concentrations up to 500 μg/ml, showed no effect on the replication, yield, or infectivity of seven viruses or on the agents of psittacosis and meningopneumonitis when grown in mice or embryonated eggs. At the 500 μg/ml level, lymphogranuloma venereum cultures had a slight reduction in infectivity. Rickettsia akari demonstrated susceptibility at the 5 μg/ml level, whereas R. rickettsii, R. mooseri , and R. canada grown in embryonated eggs were susceptible in varying degrees to gentamicin at or above the 50 μg/ml concentration. |
| Databáze: | OpenAIRE |
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