Unrecognized Viral Respiratory Tract Infections in Premature Infants during their Birth Hospitalization: A Prospective Surveillance Study in Two Neonatal Intensive Care Units

Autor: Nicholas J. Bennett, Helene F. Rosenberg, Deanna L. Kiska, Dongliang Wang, Christy M. Tabarani, Danning Huang, Nadine M. Bartholoma, Joseph B. Domachowske, Scott W. Riddell, Robert Hingre
Rok vydání: 2012
Předmět:
Zdroj: The Journal of Pediatrics
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2012.05.001
Popis: Objective To determine the frequency and effects of nosocomial respiratory viral infections (RVIs) in premature neonates, including those who may be asymptomatic. Study design We performed a year-long surveillance for RVIs in infants Results Twenty-six of 50 prematurely born infants (52%) tested positive for a respiratory virus at least once during their birth hospitalization. Testing positive for a respiratory virus was significantly associated with longer length of stay (70 days vs 35 days, P = .002) and prolonged ventilatory support (51 vs 13 days, P = .002). Infants who tested positive for a respiratory virus during their birth hospitalization had more than twice the rate of developing bronchopulmonary dysplasia ( P Conclusion Nosocomial RVIs were frequent in our study population, despite the absence of clinical indicators of illness. Length of hospital stay was significantly longer and a diagnosis of bronchopulmonary dysplasia was more common in infants who had respiratory viruses detected.
Databáze: OpenAIRE