Quadruple Vessel Coronary Artery Bypass Grafting in a 14-Year-Old Child With Plasminogen Activator Inhibitor-1 4G/4G Gene Polymorphism
| Autor: | Rocco Lafaro, Joseph Giamelli, Sett Suvro, Markus Erb, Saman Yaghoubian, Draginja Cvetkovic |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Coronary Artery Disease 030204 cardiovascular system & hematology Gene mutation Coronary artery disease 03 medical and health sciences Coronary artery bypass surgery chemistry.chemical_compound Electrocardiography 0302 clinical medicine Internal medicine medicine.artery Plasminogen Activator Inhibitor 1 medicine Humans 030212 general & internal medicine Radial artery Coronary Artery Bypass Polymorphism Genetic medicine.diagnostic_test business.industry medicine.disease Surgery Anesthesiology and Pain Medicine medicine.anatomical_structure chemistry Plasminogen activator inhibitor-1 Cardiology Gene polymorphism Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | Seminars in cardiothoracic and vascular anesthesia. 20(2) |
| ISSN: | 1940-5596 |
| Popis: | Myocardial ischemia due to coronary artery disease is an extremely rare condition in childhood and adolescence. Absence of obvious serious risk factors remains a challenge to modern cardiology. We present the case of a 14-year-old boy who underwent quadruple-vessel coronary artery bypass grafting with bilateral pedicled internal mammary artery and bilateral radial artery grafting. We try to highlight a rare but important 4G variant PAI-1 (SERPINE 1) gene mutation as the etiology of severe coronary artery disease in our patient. To the best of our knowledge, he is one of the youngest patients who underwent coronary artery bypass surgery with 4 arterial grafts. |
| Databáze: | OpenAIRE |
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