No survival advantage exists for patients undergoing loop ileostomy for clostridium difficile colitis

Autor: Dmitry Oleynikov, Bradley R. Hall, Priscila R. Armijo, Lynette M. Smith, Sean J. Langenfeld, Jennifer A. Leinicke
Rok vydání: 2019
Předmět:
Zdroj: The American Journal of Surgery. 217:34-39
ISSN: 0002-9610
DOI: 10.1016/j.amjsurg.2018.09.023
Popis: We aim to compare outcomes between loop ileostomy (LI) and total abdominal colectomy (TAC) for clostridium difficile infection (CDI) and hypothesize that LI is associated with fewer complications.The 2011-2016 ACS-NSQIP database was queried for patients undergoing LI or TAC for CDI. Patients with high outlying age, LOS, and operative time were excluded. Statistics were performed using IBM-SPSS and NCSS PASS-11.Of 457 patients identified, 47 underwent LI. Predicted morbidity was higher in the TAC cohort (62% vs. 37%, p 0.001). Patients in the LI cohort experienced fewer complications (72% vs. 87%, p = 0.021); however, mortality did not differ between LI (36%) and TAC (31%). Blood transfusions were more than twice as frequent in the TAC cohort (54% vs. 19%, p 0.001). Four patients in the LI cohort required reoperation; however, none required colectomy.No mortality difference was observed between LI and TAC. Prospective studies are required to determine the utility of LI.An analysis of the ACS-NSQIP database was performed and demonstrates that no survival benefit exists for patients who undergo loop ileostomy for C difficile infection compared to those who undergo total colectomy; however, patients who undergo loop ileostomy are likely to retain their colon with low risk of requiring subsequent colectomy.
Databáze: OpenAIRE