| Autor: |
Igor Astsaturov, Erica A. Golemis, Gail E. Herman, Louis M. Weiner, Richard I. Kelley, Lisa E. Kratz, Andres Klein-Szanto, Kathy Q. Cai, Barbara Burtness, Ranee Mehra, Dong-Hua Yang, Yan Zhou, Gregory P. Adams, Anna Nikonova, Hanqing Liu, Tetyana Bagnyukova, David Cunningham, Brian L. Egleston, Diana Restifo, Hui Zheng, Linara Gabitova, Ilya G. Serebriiskii, Andrey Gorin, Anna Sukhanova |
| Rok vydání: |
2023 |
| Popis: |
PDF file - 1.2MB, Fig. S1. Validation of the sterol pathway targeting siRNA. Fig. S2. Silencing of SC4MOL increased erlotinib-induced apoptosis. Fig. S3. Metabolic effects of SC4MOL silencing and sterols supplementation. Fig. S4. Sterol pathway interactions. Fig. S5. Effects of SC4MOL silencing on EGFR synthesis and I-125 EGF internalization and degradation. Fig. S6. Effects of sterol pathway genes silencing on EGFR endosomal traffic. Fig. S7. Effects of SC4MOL silencing on EGFR ubiquitin conjugation and accumulation in late endosomes. Fig. S8. Supporting data for Figure 5. Fig. S9. Supporting data for Figure 7A. Fig. S10. Analysis of NSDHL expression in malignant and benign epithelial tissues |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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