A randomized controlled trial of the safety and efficacy of preoperative rectal misoprostol for prevention of intraoperative and postoperative blood loss at elective cesarean delivery
| Autor: | Tarek Fawzi, Wesam S. Deeb, Ahmed Said Ali, Bahaa Eldin M. Hammad, Ahmed Samy, Mohamed A. Shalaby, Ahmed M. Maged, Mohamed A. Rabee, Eman A. Hussein |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Randomization Postoperative Blood Loss law.invention Blood loss Randomized controlled trial law Administration Rectal Pregnancy Oxytocics Elective Cesarean Delivery medicine Humans Single-Blind Method Hematocrit levels Postoperative Period Misoprostol business.industry Cesarean Section Postpartum Hemorrhage Obstetrics and Gynecology General Medicine Anesthesia Rectal administration Female business medicine.drug |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and ObstetricsREFERENCES. 147(1) |
| ISSN: | 1879-3479 0368-0339 |
| Popis: | OBJECTIVE To assess the safety and efficacy of preoperative rectal misoprostol for the prevention of intraoperative and postoperative blood loss in women undergoing elective cesarean delivery. METHODS A single-blind randomized controlled trial of 200 full-term pregnant women scheduled for elective cesarean delivery. Computer-generated randomization allocated women to receive 400 μg rectal misoprostol at urinary catheter insertion plus 400 μg rectally after abdominal closure (preoperative group, n=100) or 800 μg of rectal misoprostol after abdominal closure (postoperative group, n=100). Primary outcome was intraoperative blood loss. RESULTS Intraoperative blood loss was significantly lower in the preoperative misoprostol group compared with the postoperative group (528.7 ± 114.8 mL vs 788.6 ± 165.8 mL; P |
| Databáze: | OpenAIRE |
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