CABG Surgery Remains the best Option for Patients with Left Main Coronary Disease in Comparison with PCI-DES: Meta-Analysis of Randomized Controlled Trials
| Autor: | Rodrigo Gusmão Albuquerque Miranda, Alexandre Motta de Menezes, Frederico Pires Vasconcelos Silva, Artur Freire Soares, Michel Pompeu Barros de Oliveira Sá, Ricardo de Carvalho Lima, Mayara Lopes Araújo |
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| Rok vydání: | 2017 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty medicine.medical_treatment lcsh:Surgery Coronary Artery Disease Review Article 030204 cardiovascular system & hematology law.invention 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Randomized controlled trial law Internal medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Myocardial infarction Coronary Artery Bypass Stroke Randomized Controlled Trials as Topic business.industry Percutaneous coronary intervention Drug-Eluting Stents lcsh:RD1-811 General Medicine Publication bias medicine.disease surgical procedures operative lcsh:RC666-701 Relative risk Meta-analysis Conventional PCI Cardiology Stents Surgery Cardiology and Cardiovascular Medicine business Meta-Analysis |
| Zdroj: | Brazilian Journal of Cardiovascular Surgery v.32 n.5 2017 Brazilian Journal of Cardiovascular Surgery Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) instacron:SBCCV Brazilian Journal of Cardiovascular Surgery, Vol 32, Iss 5, Pp 408-416 |
| ISSN: | 1678-9741 0102-7638 |
| Popis: | Objective: To compare the safety and efficacy of coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) using drug-eluting stents (DES) in patients with unprotected left main coronary artery (ULMCA) disease. Methods: MEDLINE, EMBASE, CENTRAL/CCTR, SciELO, LILACS, Google Scholar and reference lists of relevant articles were searched for clinical studies that reported outcomes at 1-year follow-up after PCI with DES and CABG for the treatment of ULMCA stenosis. Five studies fulfilled our eligibility criteria and they included a total of 4.595 patients (2.298 for CABG and 2.297 for PCI with DES). Results: At 1-year follow-up, there was no significant difference between CABG and DES groups concerning the risk for death (risk ratio [RR] 0.973, P=0.830), myocardial infarction (RR 0.694, P=0.148), stroke (RR 1.224, P=0.598), and major adverse cerebrovascular and cardiovascular events (RR 0.948, P=0.680). The risk for target vessel revascularization (TVR) was significantly lower in the CABG group compared to the DES group (RR 0.583, P |
| Databáze: | OpenAIRE |
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