Continuous glucose monitoring in youth with type 1 diabetes: 12-month follow-up of the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized trial
| Autor: | H. Peter Chase, Lori M.B. Laffel, Katrina J. Ruedy, Julie Coffey, Craig Kollman, Dongyuan Xing, Roy W. Beck, William V. Tamborlane, Joyce Keady, Brett Ives, Larry A. Fox |
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| Rok vydání: | 2010 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Pediatrics endocrine system diseases Adolescent Endocrinology Diabetes and Metabolism Monitoring Ambulatory Statistics Nonparametric law.invention Hba1c level Endocrinology Randomized controlled trial law Diabetes mellitus Surveys and Questionnaires Medicine Humans Longitudinal Studies Intensive care medicine Child Glycated Hemoglobin Type 1 diabetes business.industry Continuous glucose monitoring nutritional and metabolic diseases medicine.disease Severe hypoglycemia Medical Laboratory Technology Diabetes Mellitus Type 1 Patient Satisfaction Female business Pediatric population Month follow up |
| Zdroj: | Diabetes technologytherapeutics. 12(7) |
| ISSN: | 1557-8593 |
| Popis: | The use of continuous glucose monitoring (CGM) in the pediatric population is not well characterized. We have evaluated the use of CGM over a 12-month interval in youth with type 1 diabetes (TID) and have provided a description of CGM use.Eighty subjects 8-17 years old with T1D and baseline hemoglobin A1c (HbA1c)or=7.0% used CGM as part of a 6-month randomized trial and subsequent 6-month extension study. Outcomes included frequency of CGM use, HbA1c levels, rate of severe hypoglycemia, and a CGM satisfaction scale.Seventy-six (95%) of 80 subjects were using CGM after 6 months (median use = 5.5 days/week) compared with 67 (84%) after 12 months (median use = 4.0 days/week). The 17 subjects using CGMor=6 days/week in month 12 had substantially greater improvement from baseline in HbA1c than did the 63 subjects using CGM6 days/week in month 12 (mean change - 0.8 +/- 0.6% vs. +0.1 +/- 0.7%, P0.001). They also reported greater satisfaction with use of CGM (P = 0.001). The incidence of severe hypoglycemic events was low during the 12 months of the study irrespective of the amount of CGM use.In youth with T1D, frequency of use decreases over time. Individuals who use CGM on a near-daily basis can have substantial improvement in glycemic control. |
| Databáze: | OpenAIRE |
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