Alkaline Intraoesophageal pH and Gastro-oesophageal Reflux in Patients with Peptic Oesophagitis
| Autor: | H. Yuen, Roberto Penagini, J.J. Misiewicz, Paolo A. Bianchi |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male medicine.medical_specialty Peptic medicine.medical_treatment Gastroenterology Bile reflux Esophagus Gastrectomy Gastro Internal medicine Humans Medicine Esophagitis Peptic Aged Gastric Juice business.industry Reflux Exudates and Transudates Hydrogen-Ion Concentration Middle Aged medicine.disease digestive system diseases medicine.anatomical_structure Esophageal Stenosis Female Peptic oesophagitis business Esophagitis |
| Zdroj: | Scandinavian Journal of Gastroenterology. 23:675-678 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.3109/00365528809093931 |
| Popis: | Simultaneous 22-h measurements of intra-oesophageal and intragastric pH were made in 22 patients with symptoms of gastro-oesophageal reflux (7 with peptic oesophagitis, 8 with peptic oesophageal stricture, and 7 with peptic oesophagitis and previous partial gastrectomy) to determine whether alkaline intra-oesophageal pH is a consequence of alkaline gastro-oesophageal reflux. In the three groups of patients intra-oesophageal pH was greater than 7 for 16.9 +/- 4.8%, 27.5 +/- 7.6%, and 21.0 +/- 7.7%, respectively, of total recording time (p = NS). Intragastric pH greater than 7 was recorded only in the patients with partial gastrectomy (10.3 +/- 5.3% of recording time; p less than 0.01 in comparison with the other groups). Elevations of intra-oesophageal pH to greater than 7 never occurred during episodes of alkalinization of intragastric pH. These results suggest that refluxed fluids are unlikely to be the cause of alkaline intra-oesophageal pH in patients with peptic oesophagitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|