Effect of dentin powder on the antimicrobial properties of hyperpure chlorine-dioxide and its comparison to conventional endodontic disinfecting agents
| Autor: | Milán Gyurkovics, Ágoston Ghidán, Anna Herczegh, Marianna Megyesi, Zsolt Lohinai |
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| Rok vydání: | 2014 |
| Předmět: |
Time Factors
Sodium Hypochlorite Root canal Disinfectant Smear layer Dentistry Enterococcus faecalis Calcium Hydroxide chemistry.chemical_compound stomatognathic system medicine Dentin Humans General Immunology and Microbiology biology Root Canal Irrigants business.industry Chlorhexidine Oxides General Medicine biology.organism_classification Plankton Culture Media stomatognathic diseases medicine.anatomical_structure chemistry Sodium hypochlorite Powders business Antibacterial activity Chlorine Compounds medicine.drug Nuclear chemistry |
| Zdroj: | Acta microbiologica et immunologica Hungarica. 61(2) |
| ISSN: | 1217-8950 |
| Popis: | Introduction Previously we found that the high purity chlorine-dioxide(ClO2) has a very potent disinfectant efficacy on oral pathogenic microorganisms and as a root canal irrigant it is able to eliminate the experimental Enterococcus faecalis(E. faecalis) infection from the root canal system. This study examines whether the presence of dentin powder influences the antibacterial efficacy of ClO 2. Methods In an in vitro dentin powder model the following irrigants were tested against planktonic E. faecalis: 2% chlorhexidine (CHX), 2.5% sodium hypochlorite (NaOCl), 0.12%ClO2 (Solumium) and one local root canal medicament: saturated Ca(OH)2. Survival of bacteria exposed to agents without and with human dentin powder or preincubated with dentin powder was investigated. The effect of the dentin powder on ClO2 concentration was investigated by titrations. Results Without dentin powder ClO 2 killed all E. faecalis and delivered the best result already after 1 minute; however, after longer contact time with dentin the difference between the disinfectants disappeared. The presence of dentin powder decreased the concentration of ClO 2 and attenuated the antibacterial efficiency of ClO2 and Ca(OH)2, but did not decrease of CHX and NaOCl.Preincubation with dentin powder caused significant loss of antibacterial activity of all investigated agents, ClO2 and Ca(OH)2 having the highest reduction. Conclusion As the presence of dentin powder had a negative effect on the efficacy of disinfectants, the importance of elimination of dentin scrapings and smear layer from the root canal system during endodontic treatments is highly recommended. ClO 2 can be effective for a final rinse. |
| Databáze: | OpenAIRE |
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