Combined therapies with nanostructured carbon materials: there is room still available at the bottom
| Autor: | Biagiotti, G. Fedeli, S. Tuci, G. Luconi, L. Giambastiani, G. Brandi, A. Pisaneschi, F. Cicchi, S. Paoli |
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| Rok vydání: | 2020 |
| Předmět: |
Graphene
Graphene derivatives Biomedical Engineering Oxide Nanoparticle Nanotechnology 02 engineering and technology General Chemistry General Medicine Carbon nanotube 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences law.invention chemistry.chemical_compound chemistry Nanostructured carbon law Drug delivery Nanomedicine General Materials Science Combined therapies 0210 nano-technology nanostructured carbon materials |
| Zdroj: | Journal of Materials Chemistry B 6 (2018). doi:10.1039/c8tb00121a info:cnr-pdr/source/autori:Biagiotti, G. Fedeli, S. Tuci, G. Luconi, L. Giambastiani, G. Brandi, A. Pisaneschi, F. Cicchi, S. Paoli, P./titolo:Combined therapies with nanostructured carbon materials: there is room still left at the bottom/doi:10.1039%2Fc8tb00121a/rivista:Journal of Materials Chemistry B/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:6 |
| ISSN: | 2050-7518 |
| DOI: | 10.1039/c8tb00121a |
| Popis: | The progress of the chemistry of carbon nanotubes (CNT) and graphene derivatives [mainly graphene oxide (GO)] has produced a number of technologically advanced drug delivery systems (DDS) that have been used in the field of nanomedicine, mostly in studies related to oncology. However, such a demanding field of research requires continuous improvements in terms of efficiency, selectivity and versatility. The loading of two, or more, bioactive components on the same nanoparticle offers new possibilities for treating cancer, efficiently addressing issues related both to biodistribution and pharmacokinetics. Nanostructured carbon materials (NCM), with their high surface area, their efficient cellular membrane crossing and their chemical versatility are ideal candidates for easy hetero-decoration and exploitation as advanced DDS. This review describes the achievements obtained in this area focusing on those studies in which two or more active components were loaded onto the DDS. |
| Databáze: | OpenAIRE |
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