In vitroantibacterial activity of medicinal plant extracts againstEscherichia colistrains from human clinical specimens and interactions with antimicrobial drugs
| Autor: | L.C. Di Stasi, Priscila Ikeda Ushimaru, Lidiane Nunes Barbosa, A. Fernandes, A. Fernandes Junior |
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| Rok vydání: | 2012 |
| Předmět: |
Syzygium
Microbial Sensitivity Tests Plant Science Ginger Biology medicine.disease_cause Biochemistry Analytical Chemistry Microbiology Minimum inhibitory concentration Sativum Anti-Infective Agents Cymbopogon citratus Escherichia coli medicine Humans Cymbopogon Mikania Garlic Medicinal plants Plants Medicinal Psidium Plant Extracts Organic Chemistry food and beverages Drug Synergism Antimicrobial biology.organism_classification Anti-Bacterial Agents Antibacterial activity Antagonism |
| Zdroj: | Natural Product Research. 26:1553-1557 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2011.568943 |
| Popis: | The biological properties of medicinal plants have been documented worldwide for many centuries. We aimed to evaluate interactions between crude extracts from Psidium guajava, Zingiber officinale, Cymbopogon citratus, Caryophyllus aromaticus, Mikania glomerata and Allium sativum samples and antimicrobial drugs against Escherichia coli strains. The susceptibility test performed was disc diffusion, and crude extracts were diluted (%v/v) into Müller-Hinton agar (MHA) at one quarter of the minimal inhibitory concentration for 90% (MIC(90%)) of E. coli strains found previously. Synergistic interactions were observed between C. citratus and polymyxin, and A. sativum extracts and gentamicin. The crude A. sativum extract was the only one that did not show any antagonism with the antimicrobial drugs. The results thus showed the potential use of these medicinal plants against E. coli strains, although antagonism with antimicrobial drugs is a negative aspect in the combined therapy of infectious diseases caused by E. coli. |
| Databáze: | OpenAIRE |
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