Polycystic ovary syndrome and depression in New Zealand adolescents
| Autor: | Cara M. Ogilvie, Joanna Stewart, Sally N Merry, Sasha M. Nair, Stella R. Milsom |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty Pediatrics endocrine system diseases Adolescent Body Mass Index Young Adult Surveys and Questionnaires Acne Vulgaris medicine Prevalence Humans Psychiatry Socioeconomic status Acne Depression (differential diagnoses) Psychiatric Status Rating Scales business.industry Depression nutritional and metabolic diseases Obstetrics and Gynecology General Medicine medicine.disease Obesity Polycystic ovary Case-Control Studies Pediatrics Perinatology and Child Health Cohort Observational study Female business Body mass index New Zealand Polycystic Ovary Syndrome |
| Zdroj: | Journal of pediatric and adolescent gynecology. 26(3) |
| ISSN: | 1873-4332 |
| Popis: | Objective To determine whether adolescents with polycystic ovary syndrome (PCOS) are more depressed than adolescent girls in the community and to examine factors associated with depression. Design An observational study comparing clinical and community samples. Setting Two specialist reproductive endocrine clinics in Auckland, New Zealand. Participants 102 girls aged 14-19 presenting for clinical assessment, fulfilling the Rotterdam consensus for PCOS. The comparison group was 1349 girls from a school-based survey of New Zealand youth. Interventions Clinically significant depression was identified by the long and short form Reynolds Adolescent Depression Scale. BMI, androgen levels, oral contraceptive use, objective symptom severity, age, ethnicity, and socioeconomic grouping were recorded. Main Outcome Measures Clinically significant depression in the PCOS and community samples. Potential determinants of depression. Results Clinically significant depression in adolescent girls with PCOS was not increased compared with the community sample (OR 1.3; 95%CI 0.7-2.7, P = .42). Within the PCOS cohort, depression was correlated with increased BMI ( P = .01) and possibly acne ( P = .08). Conclusions Lean adolescent girls with PCOS did not have more clinically significant depression than girls in the community. Within the PCOS cohort, however, there was a clear association between higher depression scores and elevated BMI. There is a potentially important interaction between obesity and depression in PCOS. |
| Databáze: | OpenAIRE |
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