Conversion of protopanaxadiol type saponins to ginsenoside Rg3 by lemon
| Autor: | Wei-ping Gao, Bao-zhong Zhao, Le-qin Cheng, Cheng-peng Sun |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pharmacology
Citrus Citrus limon Chromatography Magnetic Resonance Spectroscopy Sapogenins Ginsenosides Hydrolysis Plant Science General Medicine chemistry.chemical_compound 13c nmr spectroscopy Complementary and alternative medicine chemistry Ginsenoside Ginsenoside Rb1 Drug Discovery Proton NMR Protopanaxadiol Lemon juice |
| Zdroj: | Natural product communications. 7(9) |
| ISSN: | 1934-578X |
| Popis: | The ability of fresh lemon ( Citrus limon) to convert protopanaxadiol-type saponins into ginsenoside Rg3 was investigated, and the structures of 20( S)-ginsenoside Rg3 (1) and 20( R)-ginsenoside Rg3 (2) were identified by 1H NMR and 13C NMR spectroscopy. The experiment showed that lemon possesses the strong ability to hydrolyze ginsenosides. When protopanaxadiol-type saponins (16 mg/mL) were hydrolyzed by fresh lemon juice at 80°C for 3 hrs, the conversion ratios of ginsenoside Rb1, Rb2, Rc and Rd were 92.9%, 90.0%, 96.9% and 55.5%, respectively, and the yields of 20( S)-ginsenoside Rg3 and 20( R)-ginsenoside Rg3 were, respectively, 31.2% and 28.3%. |
| Databáze: | OpenAIRE |
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