Structure—activity relationships of synthetic methyl ursolate glycosides
| Autor: | Yasuo Tanaka, Masayuki Takechi |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Stereochemistry
Molecular Sequence Data Saponin Microbial Sensitivity Tests Plant Science Horticulture Biology Hemolysis Biochemistry Chemical synthesis Structure-Activity Relationship chemistry.chemical_compound Glycosides Molecular Biology Oleanolic acid Antibacterial agent chemistry.chemical_classification Bacteria Fungi Glycoside Biological activity General Medicine Haemolysis Triterpenes Carbohydrate Sequence chemistry Antibacterial activity |
| Zdroj: | Phytochemistry. 34:675-677 |
| ISSN: | 0031-9422 |
| Popis: | From 15 synthetic methyl ursolate glycosides, the di- and tri-glycosides showed much higher haemolytic activity than the monoglycosides. The beta-gentiobioside and the beta-maltotrioside exhibited much stronger antibacterial (Staphylococcus aureus) or antifungal (Trichophyton mentagrophytes) activity than the other glycosides. However, none of them exhibited antibacterial activity against Bacillus subtilis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|