Prior opioid exposure influences parents’ sharing of their children's CYP2D6 research results
| Autor: | Cassandra Perry, Matthew Veerkamp, Brooke M McLaughlin, Melanie F. Myers, Xue Zhang, Cynthia A. Prows, Kejian Zhang, Diane Kissell, Ingrid A. Holm |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Male Parents CYP2D6 Adolescent 030105 genetics & heredity 03 medical and health sciences Surveys and Questionnaires Genetics Medicine Humans Research result Baseline (configuration management) Child Pharmacology business.industry Middle Aged Analgesics Opioid 030104 developmental biology Opioid Cytochrome P-450 CYP2D6 Molecular Medicine Female Perception business Return of results Clinical psychology medicine.drug Research Article |
| Popis: | Aim: To determine parents’ use of their children's CYP2D6 research result. We hypothesized that perceived utility, likelihood of sharing and actual sharing of results would differ between parents with children previously exposed (cases) or unexposed (controls) to opioids. Methods: We returned results by phone (baseline). We surveyed parents about perceived utility and likelihood of sharing their child's research result at baseline, and actual sharing at 3 and 12 months. Results: Cases were more likely than controls to agree that they (p = 0.022) and the doctors (p = 0.041) could use the results to care for their child, to report higher likelihood of sharing (p = 0.042) and to actually share results with the child's doctor (p = 0.026). Conclusion: Prior opioid exposure influenced perceived clinical utility and sharing behaviors. |
| Databáze: | OpenAIRE |
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