Maintenance of anticoagulant and antiplatelet agents for patients undergoing peribulbar anesthesia and vitreoretinal surgery
| Autor: | Philippe Koehrer, Alain M. Bron, Catherine Creuzot-Garcher, André Juniot, M. Passemard |
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| Přispěvatelé: | Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand ( CHU Dijon ), Centre des Sciences du Goût et de l'Alimentation [Dijon] ( CSGA ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2012 |
| Předmět: |
Male
Eye Hemorrhage genetic structures Conscious Sedation Electrocardiography Oximetry Young adult Aged 80 and over Aspirin medicine.diagnostic_test Incidence (epidemiology) Anticoagulant General Medicine Middle Aged Clopidogrel Anesthesia [ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory Organs Female Orbit medicine.drug Adult medicine.medical_specialty Ticlopidine medicine.drug_class Postoperative Hemorrhage Vitreoretinal Surgery Young Adult [ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology medicine Humans [SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs Aged Retrospective Studies business.industry Acenocoumarol Anticoagulants Retrospective cohort study Phenindione eye diseases Surgery Ophthalmology Warfarin business [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology Platelet Aggregation Inhibitors Case series Anesthesia Local |
| Zdroj: | RETINA RETINA, Lippincott, Williams & Wilkins, 2012, 32 (9), pp.1868-1873 |
| ISSN: | 1539-2864 0275-004X |
| Popis: | PURPOSE: : To establish the prevalence of anticoagulation (vitamin K antagonists) and antiplatelet agent therapy in patients undergoing vitreoretinal surgery and to compare the outcome of peribulbar anesthesia and vitreoretinal surgery between users and nonusers. METHODS: : We conducted a retrospective case series study in one academic center. No changes in the treatment regimen were made before surgery. Patients were divided into 3 groups: G1, patients with no anticoagulant or antiplatelet therapy; G2, patients treated with anticoagulants; and G3, patients treated with aspirin, clopidogrel, or both. RESULTS: : Two hundred and six eyes (206 patients) were included. G1, 144 eyes (69.9%) without any anticoagulant or antiplatelet therapy (69.9%); G2, 12 eyes (5.8%) with anticoagulants; and G3, 44 eyes (21.4%) with antiplatelet agents. Six patients (6 eyes) (2.9%) received both anticoagulant and antiplatelet agents. The incidence of overall and mild postoperative hemorrhagic complications was similar between groups, P = 0.075 and P = 0.127, respectively. However, potential sight-threatening hemorrhagic complications were more frequent in patients receiving antiplatelet agents, P < 0.003. CONCLUSION: : Peribulbar anesthesia for vitreoretinal surgery can probably be performed safely in patients receiving anticoagulants. However, retinal surgeons should be aware that severe bleeding complications are more frequent in patients receiving antiplatelet therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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