Clinical Presentation, Autopsy Results and Toxicology Findings in an AcuteN-Ethylpentylone Fatality
| Autor: | Phoutthasone Thirakul, Julia Pearson, Laura S. Hair, Kirstin L. Bergen |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
Fever Health Toxicology and Mutagenesis Autopsy Butylamines Toxicology 01 natural sciences Analytical Chemistry law.invention Forensic Toxicology 03 medical and health sciences 0302 clinical medicine law medicine Humans Environmental Chemistry Benzodioxoles Enlarged heart Cause of death Disseminated intravascular coagulation Chemical Health and Safety business.industry 010401 analytical chemistry Forensic toxicology medicine.disease Intensive care unit Heart Arrest 0104 chemical sciences Respiratory failure Central Nervous System Stimulants business Rhabdomyolysis 030217 neurology & neurosurgery |
| Zdroj: | Journal of Analytical Toxicology. |
| ISSN: | 1945-2403 0146-4760 |
| Popis: | The clinical presentation, autopsy findings and toxicology results in an acute fatality involving N-ethylpentylone, a new cathinone derivative, are described. Law enforcement transported a male who was agitated and exhibiting unusual behavior to a local hospital. Upon arrival at the hospital, his body temperature was 105.5 degrees Fahrenheit and his blood pH was 6.7. Clinical laboratory analysis revealed elevated troponins, rhabdomyolysis, hypoglycemia, hepatic and renal injury, respiratory failure and disseminated intravascular coagulation. He was intubated and admitted to the intensive care unit, treated with cooling blankets, bicarbonate and intravenous fluids. Despite medical treatment, he went into cardiac arrest and was pronounced dead ~36 h after admission. Autopsy findings identified some abrasions on his arms and legs, a bloody nose and a mildly enlarged heart. Antemortem blood was analyzed by gas chromatography coupled with a mass spectrometer which identified N-ethylpentylone. Based on clinical presentation, autopsy findings and toxicology results, the medical examiner concluded the cause of death was intoxication by N-ethylpentylone and the manner of death was accident. |
| Databáze: | OpenAIRE |
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