Fine-needle aspiration with rapid parathyroid hormone assay to identify parathyroid gland in thyroidectomy

Autor: Xian Zou, Bin Zhou, Jun Fan, Jiandong Bao, Zhongwei Lv, Yonghong Hu, Shi Longshun, Guohua Zhu, Zhu Liguo
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
Pathology
medicine.medical_specialty
medicine.medical_treatment
Biopsy
Fine-Needle
Parathyroid Diseases
Parathyroid hormone
Diagnostic Accuracy Study
Sensitivity and Specificity
Parathyroid Glands
03 medical and health sciences
0302 clinical medicine
Hypothyroidism
Monitoring
Intraoperative
Biopsy
medicine
central compartment lymph node dissection
Humans
030212 general & internal medicine
Postoperative Period
Thyroid Neoplasms
parathyroid preservation
Thyroid cancer
Saline
Aged
medicine.diagnostic_test
business.industry
intraoperative parathyroid hormone levels
Thyroidectomy
General Medicine
Middle Aged
medicine.disease
Dissection
Fine-needle aspiration
medicine.anatomical_structure
Parathyroid Hormone
030220 oncology & carcinogenesis
Lymph Node Excision
Parathyroid gland
Female
business
hormones
hormone substitutes
and hormone antagonists
Research Article
Zdroj: Medicine
ISSN: 1536-5964
0025-7974
Popis: To determine the levels of parathyroid hormone (PTH) in the fluids of various tissues for identification of parathyroid glands during thyroidectomy. Our study comprised 31 patients with thyroid cancer who underwent lobectomy with central compartment dissection at our hospital from October 2014 to February 2015. A total of 186 tissue samples, including 28 from parathyroid glands and 158 from non-parathyroid tissues, were obtained during the operations. Tissue fluids were collected via fine-needle aspiration to measure PTH levels; the tissue was punctured 3 times with a 26-gauge syringe needle and washed with 0.5 mL normal saline. Tissues were also prepared for pathological examination. PTH concentrations were significantly higher in parathyroid tissues than non-parathyroid tissues. None of the patients had irremediable parathyroid dysfunction after surgical resection. Use of fine-needle aspiration for quantification of PTH levels in tissue fluids rapidly, safely, and effectively identifies the parathyroid glands during thyroidectomy.
Databáze: OpenAIRE
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