Low androstenedione/sex hormone binding globulin ratio increases fracture risk in postmenopausal women. The Women's Health in the Lund Area study
| Autor: | Peter M. Nilsson, Göran Samsioe, Christer Borgfeldt, Louise M.E. Moberg |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Percentile Bone density medicine.medical_treatment Osteoporosis General Biochemistry Genetics and Molecular Biology Fractures Bone Sex hormone-binding globulin Risk Factors Sex Hormone-Binding Globulin Internal medicine medicine Humans Androstenedione Osteoporosis Postmenopausal Testosterone Estradiol biology business.industry Incidence Obstetrics and Gynecology Middle Aged medicine.disease Endocrinology biology.protein Women's Health Female Hormone therapy business Cohort study |
| Zdroj: | Maturitas. 75:270-275 |
| ISSN: | 0378-5122 |
| DOI: | 10.1016/j.maturitas.2013.04.010 |
| Popis: | The Women's Health in the Lund Area (WHILA) project (n=6917) is a cohort study that started in 1995 and includes a postal questionnaire, physical examination, bone density measurement and blood laboratory analyses. Fracture data have been added, and in this report fracture risk and its association with sex hormones was analysed in postmenopausal women without current hormone therapy (HT). A total of 409 women (median age 56.8 years) with 489 fractures were identified from the postmenopausal women without HT during a median follow-up time of 8.4 years. Lower serum levels of androstenedione (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect