Oxidations catalyzed by phenylacetone monooxygenase from Thermobifida fusca
| Autor: | Gonzalo de Gonzalo, Gianluca Ottolina, Marco W. Fraaije, Giacomo Carrea, Daniel E. Torres Pazmino |
|---|---|
| Přispěvatelé: | Groningen Biomolecular Sciences and Biotechnology |
| Rok vydání: | 2005 |
| Předmět: |
BAEYER-VILLIGER OXIDATIONS
4-HYDROXYACETOPHENONE MONOOXYGENASE Redox Catalysis Inorganic Chemistry chemistry.chemical_compound HYDROGEN-PEROXIDE ASYMMETRIC OXIDATION Organic chemistry Reactivity (chemistry) Physical and Theoretical Chemistry Hydrogen peroxide ENANTIOSELECTIVE OXIDATION CHIRAL BENZYL ALKYL Phenylacetone monooxygenase chemistry.chemical_classification SULFIDE OXIDATIONS Chemistry CYCLOHEXANONE MONOOXYGENASE Organic Chemistry General Medicine Monooxygenase Enzyme DISPLACEMENT REACTIONS Biocatalysis Amine gas treating SYNTHETIC APPLICATIONS |
| Zdroj: | Tetrahedron: asymmetry 16 (2005): 3077–3083. doi:10.1016/j.tetasy.2005.08.004 info:cnr-pdr/source/autori:de Gonzalo G., Pazmino D.E.T., Ottolina G., Fraaije M.W., Carrea G./titolo:Oxidations catalyzed by phenylacetone monooxygenase from Thermobifida fusca/doi:10.1016%2Fj.tetasy.2005.08.004/rivista:Tetrahedron: asymmetry (Print)/anno:2005/pagina_da:3077/pagina_a:3083/intervallo_pagine:3077–3083/volume:16 Tetrahedron-Asymmetry, 16(18), 3077-3083. PERGAMON-ELSEVIER SCIENCE LTD |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/j.tetasy.2005.08.004 |
| Popis: | Several organic sulfides, ketones and other organic systems have been tested as substrates in oxidation reactions catalyzed by the recently discovered phenylacetone monooxygenase from Thermobifida fusca. The biocatalytic properties of this Baeyer–Villiger monooxygenase have been studied, revealing reactivity with a large range of sulfides and ketones. Oxidations of several sulfoxides, an amine and an organoboron compound were also observed. The enzyme is able to oxidize a number of sulfides with excellent enantioselectivity, demonstrating the catalytic potential of this novel biocatalyst. |
| Databáze: | OpenAIRE |
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