Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post-partum

Autor: Lisbeth Dahl, Marianne Sandsmark Morseth, Inger Aakre, Vibeke Moe, Lars Smith, Sigrun Henjum, Marian Kjellevold, Maria Wik Markhus
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
medicine.medical_specialty
post‐partum period
Breastfeeding
Nutritional Status
chemistry.chemical_element
Breast feeding
Iodine
03 medical and health sciences
0302 clinical medicine
Urinary iodine concentrations
Pregnancy
Thyroid dysfunction
medicine
Animals
Humans
030212 general & internal medicine
reproductive and urinary physiology
Post partum
Toddlers
030109 nutrition & dietetics
Nutrition and Dietetics
Obstetrics
business.industry
Postpartum Period
Post-partum periods
digestive
oral
and skin physiology
Public Health
Environmental and Occupational Health
Obstetrics and Gynecology
Pregnancies
Original Articles
urinary iodine concentration
medicine.disease
Iodine deficiency
female genital diseases and pregnancy complications
Iodine intake
Milk
Increased risk
chemistry
Pediatrics
Perinatology and Child Health
Original Article
Female
business
Zdroj: Maternal & Child Nutrition
ISSN: 1740-8695
Popis: Iodine deficiency during pregnancy and in the post‐partum period may lead to impaired child development. Our aim is to describe iodine status longitudinally in women from pregnancy until 18 months post‐partum. Furthermore, we explore whether iodine status is associated with dietary intake, iodine‐containing supplement use and breastfeeding status from pregnancy until 18 months post‐partum. We also assess the correlation between maternal iodine status 18 months post‐partum and child iodine status at 18 months of age. Iodine status was measured by urinary iodine concentration (UIC) during pregnancy (n = 1,004), 6 weeks post‐partum (n = 915), 6 months post‐partum (n = 849), 12 months post‐partum (n = 733) and 18 months post‐partum (n = 714). The toddlers' UIC was assessed at 18 months of age (n = 416). Demographic variables and dietary data (food frequency questionnaire) were collected during pregnancy, and dietary data and breastfeeding practices were collected at all time points post‐partum. We found that iodine status was insufficient in both pregnant and post‐partum women. The UIC was at its lowermost 6 weeks post‐partum and gradually improved with increasing time post‐partum. Intake of milk and use of iodine‐containing supplements significantly increased the odds of having a UIC above 100 μg/L. Neither the mothers' UIC, vegetarian practice, nor exclusion of milk and dairy products were associated with the toddlers UIC 18 months post‐partum. Women who exclude milk and dairy products from their diets and/or do not use iodine‐containing supplements may be at risk of iodine deficiency. The women possibly also have an increased risk of thyroid dysfunction and for conceiving children with nonoptimal developmental status. The Research Council of Norway (Grant 196156) and the Norwegian Seafood Research Fund, FHF (Grant 900842) supported the work.
Databáze: OpenAIRE
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