Three-dimensional comparison of mandibular morphology in young people with Treacher Collins syndrome and Pierre Robin sequence
| Autor: | Priscila Padilha Moura, Cristiano Tonello, Adriano Porto Peixoto, Daniela Gamba Garib, Renata Mayumi Kato, Roseli Maria Zechi-Ceide |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Adolescent Cephalometry Orthodontics Mandible Condyle SÍNDROME DE PIERRE ROBIN Imaging Three-Dimensional stomatognathic system Statistical significance medicine Humans Gonial angle Child Retrospective Studies Robin Sequence Pierre Robin Syndrome business.industry fungi Mandibular morphology medicine.disease Mandibular deficiency Female business Treacher Collins syndrome Mandibulofacial Dysostosis |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Introduction Treacher Collins syndrome (TCS) and nonsyndromic Pierre Robin sequence (PRS) share mandibular deficiency as a similar clinical finding. This study aimed to compare the mandibular size and morphology of subjects with TCS and PRS. Methods Group TCS was composed of 17 subjects (7 male, 10 female) with a mean age of 11.5 years (standard deviation, 4.4) from a single center. Group PRS was composed of 17 subjects paired by age and sex with group TCS. Preorthodontic cone-beam computed tomography examinations of all patients were evaluated using Mimics Innovation Suite 17.0 (Materialise, Leuven, Belgium). Nine 3-dimensional measurements were performed in segmented 3D images of the mandible. Intragroup comparisons were performed using paired t tests. Intergroup comparisons were performed using analysis of variance and Tukey tests. The significance level considered was 5%. Results TCS showed a significant dimensional difference between less and more affected sides for ramus, condyles, and mandibular body. The mandibular dimensions in PRS were more symmetrical. Group TCS presented a smaller mandibular effective length and mandibular body length compared with PRS. The condyle width and height and the ramus width were also decreased in TCS. The gonial angle was greater in TCS compared with the PRS group. Conclusions Young subjects with TCS presented a smaller, more vertical, and more asymmetrical mandible compared with nonsyndromic PRS. |
| Databáze: | OpenAIRE |
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