Polycystic ovary syndrome and the risk of cardiometabolic complications in longitudinal studies
| Autor: | Irina Kowalska, Małgorzata Jacewicz-Święcka |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Type 2 diabetes Body Mass Index Cohort Studies Impaired glucose tolerance 03 medical and health sciences 0302 clinical medicine Endocrinology Insulin resistance Risk Factors Internal medicine Diabetes mellitus Internal Medicine medicine Humans Longitudinal Studies Prospective Studies Retrospective Studies Metabolic Syndrome 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry medicine.disease Impaired fasting glucose Polycystic ovary Observational Studies as Topic Cardiovascular Diseases Female Metabolic syndrome business Lipid profile Polycystic Ovary Syndrome |
| Zdroj: | Diabetes/Metabolism Research and Reviews. 34:e3054 |
| ISSN: | 1520-7552 |
| DOI: | 10.1002/dmrr.3054 |
| Popis: | The purpose of this study was to perform a review of the longitudinal studies to determine whether polycystic ovary syndrome is associated with higher prevalence of metabolic complications and cardiovascular morbidity and mortality. The primary outcomes included body mass index, metabolic syndrome and its components (waist circumference, lipid profile, arterial hypertension, abnormal glucose metabolism (impaired fasting glucose, impaired glucose tolerance, type 2 diabetes), insulin resistance, and cardiovascular diseases like stroke, angina, and coronary heart disease. Complications in pregnant women were beyond the scope of this review. PubMed database (1992-2018) was searched to identify proper publications. Finally, data from 47 articles were analysed. Studies differed in the design (prospective, retrospective, cohort, observational), research methods, polycystic ovary syndrome diagnostic criteria, studied populations, race, and ethnicity of the participants. Based on the data collected, it appears that women with polycystic ovary syndrome have higher prevalence of obesity, abdominal fat distribution, dyslipidaemia and deterioration of glucose metabolism, but increased prevalence of cardiovascular diseases is not proven. |
| Databáze: | OpenAIRE |
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