The motor cortex uses active suppression to sculpt movement
| Autor: | Peter L. Strick, Darcy M. Griffin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Agonist
0303 health sciences Antagonist muscle Multidisciplinary Movement (music) business.industry medicine.drug_class Antagonist SciAdv r-articles Neurophysiology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure medicine Primary motor cortex Muscle activity business Neuroscience 030217 neurology & neurosurgery Research Articles 030304 developmental biology Motor cortex Research Article |
| Zdroj: | Science Advances |
| ISSN: | 2375-2548 |
| Popis: | The motor cortex sculpts complex spatiotemporal patterns of output by actively turning off muscles, as well as by turning them on. Even the simplest movements are generated by a remarkably complex pattern of muscle activity. Fast, accurate movements at a single joint are produced by a stereotyped pattern that includes a decrease in any preexisting activity in antagonist muscles. This premovement suppression is necessary to prevent the antagonist muscle from opposing movement generated by the agonist muscle. Here, we provide evidence that the primary motor cortex (M1) sends a command signal that generates this premovement suppression. Thus, output neurons in M1 sculpt complex spatiotemporal patterns of motor output not only by actively turning on muscles but also by actively turning them off. |
| Databáze: | OpenAIRE |
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